open reading frame

open reading frame
Abbreviation: ORF
A sequence of nucleotides in a DNA molecule that has the potential to encode a peptide or protein: comprisesa start triplet (ATG), followed by a series of triplets (each of which encodes an amino acid), and ending with a stop codon (TAA, TAG or TGA). The term is generally applied to sequences of DNA fragments, for which no function has yet been determined. The number of ORFs provides an estimate of the number of genes transcribed from the DNA sequence.

Glossary of Biotechnology for Food and Agriculture . 2015.

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  • open reading frame — open reading frame. См. открытая рамка считывания. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Open reading frame — In molecular genetics, an open reading frame (ORF) is a DNA sequence that does not contain a stop codon in a given reading frame[1]. Normally, inserts which interrupt the reading frame of a subsequent region after the start codon, cause… …   Wikipedia

  • Open reading frame — (genetics) An open reading frame in DNA has no termination codon, no signal to stop reading the nucleotide sequence, and so may be translated into protein. * * * open read·ing frame rēd iŋ n a reading frame that does not contain a nucleotide… …   Medical dictionary

  • Open Reading Frame — Als offener Leserahmen (OLR) oder offenes Leseraster (als Übersetzung von engl. open reading frame, ORF) wird in der Genetik derjenige Bereich der DNA bzw. mRNA bezeichnet, dessen Leserahmen zwischen einem Start Codon und einem Stopp Codon liegt …   Deutsch Wikipedia

  • Open reading frame — Als offener Leserahmen (OLR) oder offenes Leseraster (als Übersetzung von engl. open reading frame, ORF) wird in der Genetik derjenige Bereich der DNA bzw. mRNA bezeichnet, dessen Leserahmen zwischen einem Start Codon und einem Stopp Codon liegt …   Deutsch Wikipedia

  • open reading frame — (ORF) A reading frame sequence not interrupted by a stop codon; it is usually determined by nucleic acid sequencing studies …   Dictionary of microbiology

  • open reading frame — A possible reading frame of DNA which is capable of being translated into protein, ie. is not punctuated by stop codons. (This capacity does not indicate per se that the ORF is translated.) …   Dictionary of molecular biology

  • open reading frame — noun : a reading frame that does not contain a nucleotide triplet which stops translation before formation of a complete polypeptide …   Useful english dictionary

  • open reading frame — noun A sequence of DNA triplets, between the initiator and terminator codons, that can be transcribed into mRNA and later translated into protein …   Wiktionary

  • Reading frame — One of the three possible ways to read a nucleotide sequence in DNA (depending upon whether reading starts with the first, second or third base in a triplet). * * * The grouping of nucleotides by threes into codons. See frame shift mutation.… …   Medical dictionary

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