T4 DNA ligase


T4 DNA ligase
An enzyme, present in bacteria infected with bacteriophage T4, which catalyses the joining (ligation) of, and repairs nicks in, duplex DNA molecules. Ligation activity requires that one DNA molecule has a 5'-phosphate group, and that the other has a free 3'-hydroxyl group.

Glossary of Biotechnology for Food and Agriculture . 2015.

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